Angela Minassian

I am an infectious diseases physician by training and lead a clinical malaria vaccine programme at the University of Oxford. This involves testing first-time-in-human vaccines against Plasmodium falciparum and Plasmodium vivax, incorporating controlled human malaria infection to test vaccine efficacy. I am passionate about building relationships and transferring skills to empower the research teams where malaria is endemic, and our trials now span Phase I-IIb in the UK, Africa (Tanzania, The Gambia and Burkina Faso) and Thailand. Using the platform of the malaria human challenge model I also conduct experimental medicine research to explore mechanisms of disease tolerance, and am developing a novel model of relapse for Plasmodium vivax. I also run clinical trials of vaccines against emerging pathogens and have an interest in developing new human challenge models of infection with which to assess new vaccines.