Equipment

The Carterra LSA XT is a high-throughput SPR platform for kinetic and epitope analysis, measuring up to 384 ligand interactions in parallel. It enables rapid characterisation of vaccines, therapeutic antibodies, and small molecules.

The Draper Group provides access to the LSA XT system for Oxford University research groups and external users.

We run established assays for antibodies interactions and T-cell receptor affinities and support experimental design, data acquisition, and analysis. Key specifications are listed below.

For enquiries, please contact: draper_lsa@paediatrics.ox.ac.uk

Carterra LSA XT specifications

High-throughput SPR platform for parallel kinetic and epitope analysis.

• Measures up to 384 ligand spots simultaneously against a single analyte
• 1 Hz sampling rate, enhanced sensitivity; detects analytes down to ~500 Da
• Generates full kinetic datasets from a 384-spot array in ~8 hours per antigen

Low sample consumption

• <1 µg antibody per ligand for kinetic arrays
• <30 µg antibody for epitope binning

Established in-house assays

• Antibody kinetics
• Epitope binning
• TCR–pMHC affinity
• Peptide epitope mapping

Additional applications

• Small molecule screening
• DNA Encoded Library screening
• Quantification assays

More information: carterra-bio.com